From Wikipedia, the free encyclopedia
The National Institute of Diabetes and Digestive and Kidney Diseases
(NIDDK), of the U.S. National Institutes of
Health, conducts and supports research on many of the most serious diseases
affecting public health. The Institute supports much of the clinical research on
the diseases of internal medicine and related subspecialty fields as well as
many basic science disciplines.
The Institute's Division of Intramural Research encompasses the broad
spectrum of metabolic diseases—including diabetes, obesity, inborn errors of
metabolism, endocrine disorders, disorders of mineral metabolism—as well as
digestive and liver diseases, nutrition, urology and renal disease, and
hematology. Basic research studies include biochemistry, biophysics, nutrition,
pathology, histochemistry, bioorganic chemistry, physical chemistry, chemical
and molecular biology, and pharmacology.
NIDDK extramural research is organized into four divisions: Diabetes,
Endocrinology and Metabolic Diseases; Digestive Diseases and Nutrition; Kidney,
Urologic and Hematologic Diseases; and Extramural Activities.
The Institute supports basic and clinical research through
investigator-initiated grants, program project and center grants, and career
development and training awards. The NIDDK also supports research and
development projects and large-scale clinical trials through contracts.
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NIDDK Office of the Director
Griffin P. Rodgers, M.D., M.B.A, M.A.C.P. is currently the director of the
NIDDK. Dr. Rodgers also serves as deputy director of NIDDK (since 2001) and as
chief of NIDDK's Molecular and Clinical Hematology Branch (since
1998).
Dr. Rodgers received his undergraduate, graduate and medical degrees from
Brown University in Providence, Rhode Island. He also has a master's degree in
business administration, with a focus on the business of medicine from Johns
Hopkins University. He did his residency and chief residency in internal
medicine at Barnes Hospital, and the St. Louis VA Hospital, respectively,
Washington University School of Medicine in St. Louis, Missouri. His fellowship
training in hematology/oncology was in a joint program of the NIH with George
Washington University and the Washington Veterans Administration Medical
Center.
Dr. Rodgers is widely recognized for his contributions to the development of
the first effective — and now FDA approved — therapy for sickle cell anemia. He
has served as the principal investigator in clinical trials to elevate
pharmacologically fetal hemoglobin to counteract the deleterious molecular and
cellular effects present in the red cells of these patients. Dr. Rodgers' basic
research has focused on understanding the molecular basis of how these drugs
induce gamma-globin gene expression and on lineage-specific differentiation of
hematopoietic stem cells. He was honored for his research with the 1998 Richard
and Hinda Rosenthal Foundation Award and the 2000 Arthur S. Fleming Award, among
others. He has published over 150 original research articles, reviews, and book
chapters and has edited two books.
Dr. Rodgers served as governor to the American College of Physicians for the
Department of Health and Human Services and is a member of the American Society
of Hematology, the American Society of Clinical Investigation, and the
Association of American Physicians. He is the chair of the Hematology
Subspecialty Board and is a member of the ABIM Board of Directors.
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Division of Intramural Research (DIR)
The Division of Intramural Research conducts research and training within the
Institute's laboratories and clinical facilities in Bethesda, Maryland, and at
the Phoenix Epidemiology and Clinical Research Branch in Arizona.
The Division has 12 Branches and 10 Laboratories that cover a wide range of
research areas. In addition, there is a section on veterinary sciences, a
section on biological chemistry, the Office of Technology Transfer, the Office
of Fellow Recruitment and Career Development, and an Administrative Management
Branch. Six core laboratories provide scientific support services to
investigators.
The Intramural Branches engage in both basic and clinical research on
diabetes, bone metabolism, endocrinology, obesity, hematology, digestive
diseases, kidney diseases, kidney transplantation and genetics. Additionally,
the Phoenix Branch develops and applies epidemiologic and genetic methods to the
study of diabetes and obesity. The tenth branch addresses mathematical modeling
of biological problems.
The Laboratories are engaged in fundamental research related to the
institute's mission in the fields of molecular biology, structural biology,
chemistry, cell biology, pharmacology, chemical physics, biochemistry,
neuroscience, and developmental biology, and mathematical modeling of biological
problems.
The Laboratory Animal Science section provides research animal support and
collaboration for institute research programs. The six core laboratories provide
services to interested NIDDK scientists in the areas of proteomics and mass
spectrometry, microarray, chemical biology, mouse metabolism/transgenic support,
biotechnological support, and knockout mice.
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Division of Extramural Activities (DEA)
The Division of Extramural Activities (DEA) is responsible for coordinating
the receipt, referral and scientific review of extramural research applications
and proposals before funding, and for the processing of awards for grants,
cooperative agreements and contracts. It logs in, assigns and internally
distributes all extramural applications and proposals received by the NIDDK, and
conducts scientific and technical peer review for grant applications and
contract proposals requiring special programmatic consideration. The DEA also
manages an acquisitions and general contracting service center that services
NIDDK and several other NIH Institutes/Centers as well. The DEA also coordinates
the Institute’s Committee Management Activities and the meetings of the National
Diabetes and Digestive and Kidney Diseases Advisory Council. Finally, the DEA
performs and coordinates programmatic analysis and evaluation
activities.
Organizationally the Division has three primary functional components: The
Grants Management Branch is the focal point for all business-related
activities associated with the negotiation, award, and administration of grants
and cooperative agreements within the NIDDK.
The Scientific Review Branch coordinates the initial scientific peer
review of applications submitted in response to Request for Applications (RFAs),
training and career awards, program projects, multi-center clinical trials and
research contracts, including Loan Repayment Program applications. Most R01s,
R21s, Fellowship and SBIR grant applications are reviewed in the Center for
Scientific Review.
The Office of Acquisitions plans, organizes, directs, awards, and
administers a comprehensive acquisition program for three Institutes and one
Center: NIDDK, the National Institute of Child Health and Human Development
(NICHD); the National Institute on Alcohol Abuse and Alcoholism (NIAAA); and the
John E. Fogarty International Center (FIC).
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Division of Diabetes, Endocrinology and Metabolic
Diseases (DDEM)
The DEMD supports research and research training related to diabetes
mellitus, endocrinology, and metabolic diseases including cystic fibrosis. In
addition, DEMD leads the administration of the Trans-NIH Diabetes Program and
coordinates federally supported diabetes-related activities.
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Division of Digestive Diseases and Nutrition
(DDDN)
This division supports research related to liver and biliary diseases,
pancreatic diseases, gastrointestinal diseases, including neuroendocrinology,
motility, immunology, and digestion in the GI tract, nutrient metabolism,
obesity, eating disorders, and energy regulation. The division provides
leadership in coordinating activities related to digestive diseases and
nutrition throughout the NIH and with various other Federal agencies.
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Division of Kidney, Urologic and Hematologic Diseases
(DKUH)
The division supports research on diseases of the kidney, genitourinary
tract, and blood and blood-forming organs, and on the fundamental biology
relevant to these organ systems. It funds training and professional development
of investigators in disciplines critical for research in these areas.
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Health Education and Information Services
National Diabetes Information Clearinghouse (NDIC)
National
Digestive Diseases Information Clearinghouse (NDDIC)
National Kidney
and Urologic Diseases Information Clearinghouse (NKUDIC)
The three clearinghouses serve as information resources for patients, the
public, and health professionals concerned with diabetes, digestive diseases,
and kidney and urologic diseases. Each was authorized by Congress to increase
knowledge and understanding about these areas through the effective
dissemination of information. The NDIC was authorized by Congress in 1976, the
NDDIC in 1980, and the NKUDIC in 1987.
The clearinghouses answer inquiries; develop, print and distribute
publications; and work closely with professional and patient-advocacy
organizations and U.S. Government agencies to coordinate informational resources
about diabetes, digestive diseases, and kidney and urologic
diseases.
The clearinghouses also develop and maintain a free, online bibliographic
database of reference materials, audiovisuals, educational materials, and
“fugitive” literature in its Reference Collection, as well as an image library
of free non-copyrighted images, and linkages to relevant interactive
resources.
The clearinghouses provide two campaigns to increase awareness and action for
people with underdiagnosed or undertreated conditions: celiac disease and
bladder control issues in women.
Addresses are:
NDIC, 1 Information Way, Bethesda, Maryland 20892-3560,
phone: 1-800-860-8747;
NDDIC, 2 Information Way, Bethesda, Maryland
20892-3570, phone: 1-800-891-5389;
NKUDIC, 2 Information Way, Bethesda,
Maryland 20892-3580, phone: 1-800-891-5390.
National Diabetes Education Program (NDEP)
The NDEP, co-sponsored
by the NIDDK and the Centers for Disease Control and Prevention (CDC), is
focused on improving the treatment and outcomes for people with diabetes,
promoting early diagnosis, and ultimately preventing the onset of diabetes. The
goal of the program is to reduce the morbidity and mortality associated with
diabetes through public awareness and education activities targeted to the
general public, especially those with at risk for type 2 diabetes, people with
diabetes and their families, health care providers, and policy makers and
payers. These activities are designed to 1) increase public awareness that
diabetes is a serious, common, costly, and controllable disease that has
recognizable symptoms and risk factors; 2) encourage people with diabetes, their
families, and their social support systems to take diabetes seriously and to
improve practice of self-management behaviors; 3) reduce disparities in health
in racial and ethnic populations disproportionately affected by diabetes and 4)
alert health care providers to the seriousness of diabetes, effective strategies
for its prevention and control, and the importance of a team care approach to
helping patients manage the disease. Toward these ends, the NDEP develops
partnerships with organizations concerned about diabetes and the health care of
its constituents.
Contact information for the program is as follows:
1 Diabetes
Way
Bethesda, Maryland 20892-3600
Phone 800-438-5383.
National Kidney Disease Education Program (NKDEP)
The NKDEP
addresses the growing problem of kidney disease in this country and aims to
reduce the morbidity and mortality caused by kidney disease and its
complications. The program is dedicated to raising awareness of the seriousness
of kidney disease and its risk factors, the importance of testing those at high
risk, and the availability of treatment to prevent or slow the progression of
kidney disease to kidney failure.
Contact information for the program is as follows:
National Kidney Disease
Education Program
3 Kidney Information Way
Bethesda, MD 20892
Toll free
1-866-4-KIDNEY (1-866-454-3639)
Fax: 301-402-8182
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Weight-control Information Network
The WIN is a national information service of the National Institute of
Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of
Health (NIH). WIN was established in 1994 to provide health professionals and
consumers with science-based information on obesity, weight control, and
nutrition. WIN has also developed the Sisters Together: Move More, Eat
Better Media program that encourages Black women 18 and over to maintain a
healthy weight by becoming more physically active and eating healthier
foods.
Contact information for WIN is as follows:
The Weight-control Information
Network
1 WIN Way, Bethesda, Maryland 20892-3665
Toll-free number:
1-877-946-4627
Fax: 202-828-1028
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External links
3 Comments:
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